Principal Scientist - Process Modelling

Introduction to role:

Are you ready to lead the charge in revolutionizing pharmaceutical processes? We are seeking a Principal Scientist in Process Modelling to design, develop, and deploy cutting-edge mechanistic, hybrid, and data-driven modelling solutions. Your expertise will drive the advancement of manufacturing process modelling for active pharmaceutical ingredients, ensuring the effective utilization of modelling and simulation in process development. Collaborate with internal and external partners to foster innovation and nurture scientific growth across the modelling function. Are you up for the challenge?

Accountabilities:

- Design, develop, and deploy mechanistic, hybrid, and data-driven modelling solutions for a broad portfolio of pharmaceutical processes, including unit operations and continuous processes.
- Drive digital design strategy and utilize models and digital tools in regulatory submissions.
- Use programming languages such as Python, MATLAB, and R to translate complex mathematical models into reusable code elements.
- Develop mathematical models using engineering, chemical, or materials science knowledge and translate them into computer models using platforms like gPROMS, Aspen, DynoChem, and ANSYS.
- Implement process modelling in established workflows and document progress through scientific communication, maintaining current knowledge of new modelling techniques.

Essential Skills/Experience:

- Possession of a significant scientific background with a higher degree or PhD level education linked to predictive-modelling chemical approaches
- Evidence of development of chemical models sufficient to develop ‘right, for right now’ thinking and a life cycle management perspective
- Excellent interpersonal skills with a proven ability to engage and collaborate across boundaries, displaying a problem-solving approach and a focus on delivering results
- Highly experienced in influencing and stakeholder management
- Able to work in a global, multi-cultural business environment

Desirable Skills/Experience:

- Experience with ‘Enterprise Architecture’ data structures and how to align to them
- Experience of working with external partners/suppliers 
- Experience leading a team and developing others through coaching and mentoring
- Understanding of lean principles and demonstrated ability to drive continuous improvements

When we put unexpected teams in the same room, we unleash bold thinking with the power to inspire life-changing medicines. In-person working gives us the platform we need to connect, work at pace and challenge perceptions. That's why we work, on average, a minimum of three days per week from the office. But that doesn't mean we're not flexible. We balance the expectation of being in the office while respecting individual flexibility. Join us in our unique and ambitious world.

At AstraZeneca, we embrace change and innovation to deliver life-changing medicines quickly and sustainably. Our commitment to technology transforms our ways of working, creating smart factories that enhance efficiency across all parts of the business. With a diverse workforce united by curiosity, we leverage data to improve processes and deliver better outcomes for patients. Be part of our digital journey as we make a significant impact on society, the planet, and our business.

Ready to make a difference? Apply now and join us on this exciting journey!

AstraZeneca embraces diversity and equality of opportunity. We are committed to building an inclusive and diverse team representing all backgrounds, with as wide a range of perspectives as possible, and harnessing industry-leading skills. We believe that the more inclusive we are, the better our work will be. We welcome and consider applications to join our team from all qualified candidates, regardless of their characteristics. We comply with all applicable laws and regulations on non-discrimination in employment (and recruitment), as well as work authorization and employment eligibility verification requirements.

AstraZeneca embraces diversity and equality of opportunity. We are committed to building an inclusive and diverse team representing all backgrounds, with as wide a range of perspectives as possible, and harnessing industry-leading skills. We believe that the more inclusive we are, the better our work will be. We welcome and consider applications to join our team from all qualified candidates, regardless of their characteristics. We comply with all applicable laws and regulations on non-discrimination in employment (and recruitment), as well as work authorisation and employment eligibility verification requirements.